AK Lofquist, KM Mohler, PR Baum… - US Patent …, 2011 - freepatentsonline.com This disclosure provides a multi-target fusion protein composed of a TNF-α antagonist domain and another binding domain antagonistic for a heterologous target, such as IL6, RANKL, IL7, IL17A/F, TWEAK, CSF2, IGF1, IGF2 or BLyS/APRIL, or agonistic for a heterologous target, ... Cached
AK Lofquist, PR Baum… - US Patent …, 2011 - freepatentsonline.com This disclosure provides a multi-target fusion protein composed of a TGF? antagonist domain and another binding domain antagonistic for a heterologous target (such as IL6, IL10, VEGF, TNF, HGF, TWEAK, IGF) or agonistic for a heterologous target (such as GITR). The multi- ... Cached
[HTML] from uq.edu.auTV Arumugam - 2011 - espace.library.uq.edu.au Ischaemia-reperfusion (I/R) injury is a common clinical event with the potential to seriously affect, and sometimes kill, the patient. I/R injury develops from many clinical situations including occlusion of blood vessels, transplantation of organs, operations using tourniquets and ... Cached
M Miyazaki, RR Rivera, K Miyazaki, YC Lin… - Nature …, 2011 - nature.com It is established that the transcription factor E2A and its antagonist Id3 modulate the checkpoints consisting of the precursor to the T cell antigen receptor (pre-TCR) and the TCR. Here we demonstrate that Id3 expression was higher beyond the pre-TCR checkpoint, remained high in naive T ...